Increased Resistance of Breast, Prostate, and Embryonic Carcinoma Cells against Herpes Simplex Virus in Three-Dimensional Cultures
Figure 3
Morphology (a, c, e, and g) and GFP expression indicative of HSV-1 infection (b, d, f, and h) in two-dimensional MCF-10A, MB-231, PC-3, and P19 cultures 2 to 3 days after HSV-1 K26GFP inoculation. Wide spread GFP expression consistent with extensive virus replication was detected in MCF-10A (b) and PC-3 cultures (f). Moderate and low numbers of GFP-expressing cells were detected in MB-231 (d) and P19 cells (h), respectively. Magnification: 100x.
