International Scholarly Research Notices

Research Article

Sulfonamide Based β-Carbonic Anhydrase Inhibitors: 2D QSAR Study

Observed and predicted biological activity of -CAIs by 2D QSAR model-2.


Molecule no.	Biological activity in	Predicted activity in for 2D QSAR model-2	Molecule no.	Biological activity in	Predicted activity in for 2D QSAR model-2

a1	−0.344717	−0.03583	P10	1.266859	1.259637
a2	−0.190249	−0.882354	P11	1.120772	1.091515
a4	−0.082413	−0.080626	P12	1.272709	1.060481
a5	0.464319	−0.106191	P13	1.272709	1.026872
a6	−0.30816	−0.044932	P14	0.788528	0.89279
a7	−0.263988	−0.504471	P15	2.308512	2.124939
a8	0.11921	−0.093422	u1	−0.190249	−0.03583
a9	0.13413	−0.128722	u2	0.632479	0.403403
a10	0.1422	0.38934	u3	0.67832	0.262013
a11	0.153019	0.143271	u4	−0.439697	−0.598791
a14	−0.19505	−0.786396	u5	1.136967	1.375718
a15	−0.040293	0.058489	u6	1.153646	1.207608
a16	−0.532544	0.079877	u7	1.162552	1.346787
a17	−0.068149	−0.136086	u8	1.174377	1.371611
a18	−0.35595	−0.038223	u9	0.95411	1.21467
a19	0.046485	−0.117271	u10	1.275984	1.232844
a20	0.085669	0.138466	u11	2.121827	1.420216
a23	0.174574	−0.04454	u12	0.525091	0.153663
a25	0.112519	−0.111599	u13	1.456193	1.536107
a26	−0.284564	0.416801	u14	−0.192447	−0.537819
a27	0.150512	0.064997	u15	−0.054696	0.449772
a41	−0.240392	−0.082426	u16	1.116353	1.301899
p1	0.750809	1.070581	u17	0.81894	1.295849
p2	1.106582	1.107905	u18	1.326855	1.338187
p3	1.258037	1.366532	u19	0.900615	1.271646
p4	1.258037	1.283997	u20	0.752133	0.486782
p5	1.104543	1.327902	u22	1.116085	0.527244
p6	1.255928	1.267606	u23	1.316884	1.396856
P7	1.255928	1.21467	u24	1.006908	1.274088
P8	1.115113	1.267606	u27	1.65065	1.181115
p9	1.266859	1.283997	u28	1.151463	1.143876