Review Article
Models for the Study of Whole-Body Glucose Kinetics: A Mathematical Synthesis
Table 6
Example literature values of the three-pool model for describing glucose kinetics.
| | Reference | Population (species);
per group; body weight (kg) | Experimental groups/conditions | Isotope |
(L/kg%) | Fractional rate constant
(min−1) |
Compartment size
(mg kg−1) | | | | | | | | | | | | | |
| | [36] | Human; 6;
BW not reported | Clamped euglycemia | 3-3H | 4.13 | 1.09 ± 0.37 | 0.46 ± 0.08 | 0.019 ± 0.006 | 0.006 ± 0.003 | 0.12 ± 0.02 | 0.047 ± 0.014 | 40 ± 8 | 91 ± 30 | 96 ± 24 | | | | EHC | 3-3H | 4.56 ± 1.06 | 1.03 ± 0.58 | 0.61 ± 0.3 | 0.027 ± 0.004 | 0.035 ± 0.006 | 0.29 ± 0.1 | 0.026 ± 0.013 | 40 ± 10 | 61 ± 12 | 190 ± 74 |
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EHC, euglycemic hyperinsulinemic clamp; data are presented as mean ± SE.
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