International Journal of Proteomics

Review Article

Serum Biomarkers Identification by Mass Spectrometry in High-Mortality Tumors

Table 1

ovarian cancer serum biomarkers identified after MS-based studies.
Putative ovarian cancer biomarkerExpression in ovarian ca seraReferences
Apolipoprotein IDecreased[36, 41]
Transthyretin Decreased[36, 41]
Inter-α-trypsin inhibitor heavy chain H4 (cleavage fragment)Increased[36]
Haptoglobin-α chainIncreased[42]
Haptoglobin I precursorIncreased[43]
Fibrinopeptide AIncreased[44]
Serum amyloid A1Increased[45]
Hemoglobin α and β chainIncreased[41, 46]
TransferrinDecreased[41]
Keratin 2aIncreased[47]
Glycosyltransferase-like 1BIncreased[47]
Complement component 3 precursorDecreased[47]
Complement component 4A preproteinDecreased[47]
Casein kinase II alpha 1 subunit isoform aDecreased[47]
D-amino-acid oxidaseDecreased[47]
Transgelin 2Increased[47]
Inter-alpha (globulin) inhibitor H4Increased[47]
Fibrinogen, alpha chain isoform alpha preproteinIncreased[47]
CC2 motif ligand 18 (CCL18)Increased[48]
CXC motif ligand 1 (CXCL1)Increased[48]
Connective tissue-activating peptide III (CTAPIII)Decreased[49]
Platelet factor 4 (PF4)Decreased[49]