Clinical Study

Improved Insulin Sensitivity during Pioglitazone Treatment Is Associated with Changes in IGF-I and Cortisol Secretion in Type 2 Diabetes and Impaired Glucose Tolerance

Table 1

Subject characteristics and medications prior to pioglitazone treatment (mean ± SEM).

T2D ( )IGT ( )

Age (years) 0.031
Weight (kg) 0.436
BMI (kg/m2) 0.105
Waist circumference (cm) 0.315
Systolic blood pressure (mmHg) 0.138
Diastolic blood pressure (mmHg) 0.040
Triglycerides (mmol/L) 0.073
Low-density lipoprotein (mmol/L) 0.723
High-density lipoprotein (mmol/L) 0.624
Gamma-GT ( kat/L) 0.233
HbA1c (mmol/mol) ( ) 0.006
Duration of disease (years) n.a.n.a.

Metformin ( )6
Repaglinide ( )1
Acarbose ( )1
Low-dose aspirin ( )11
Statin ( )32
ACE-inhibitor ( )22
Angiotensin receptor blocker ( )12
Thiazide diuretic ( )11
Beta-blocker ( )1