Clinical Study

Somatosensory and Pharyngolaryngeal Auras in Temporal Lobe Epilepsy Surgeries

Table 3

Baseline characteristics of patients in the SSA/PVSA group and controls.

VariableSSA/PVSA ( = 11)Controls ( = 147) -value

Demographic
Female sex8 (72.7%)66 (44.9%)0.095
Age at surgery (yrs)40.1833.440.049
Duration of epilepsy (yrs)26.9120.840.086
Seizure characteristics
Daily seizures or worse2 (18.2%)38 (25.9%)0.649
Early ictal symptoms suggestive of insular involvement
 Epigastric symptoms6 (54.5%)54 (36.7%)0.280
 Motor symptoms4 (36.4%)16 (10.9%)0.022
 Auditory symptoms0 (0%)7 (4.8%)1.000
 Cephalic symptoms1 (9.1%)27 (18.4%)0.572
 Dysphasic symptoms0 (0%)7 (4.8%)1.000
Generalized seizures7 (63.6%)94 (63.9%)1.000
Status epilepticus1 (9.1%)6 (4.1%)0.296
Number of AEDs tried5.00 4.36 ( = 144)0.280
Left side5 (45.5%)91 (61.9%)0.292
Etiology
 History of CNS infection4 (36.4%)16 (10.9%)0.022
 History of head trauma0 (0%)12 (8.2%)1.000
 Family history1 (9.1%)32 (21.8%)0.406
 Febrile seizures1 (9.1%)33 (22.4%)0.405
 Perinatal complications1 (9.1%)9 (6.1%)0.374
 Developmental delay1 (9.1%)9 (6.1%)0.374
imaging
 Normal MRI0/10 (0%)15/104 (14.4%)0.301
 Hippocampal atrophy2/10 (20%)20/104 (19.2%)1.000
 Hippocampal atrophy and sclerosis6/10 (60%)48/104 (46.2%)0.466
Other temporal lesion5 (45.5%)46 (31.3%)0.270
Scalp EEG
 Localizing to TL7 (63.6%)81/144 (56.3%)0.690
 Lateralizing3 (27.3%)34/144 (23.6%)0.641
 Nonlateralizing 1 (9.1%)29/144 (20.1%)0.615
SPECT localizing to TL2/7 (28.6%)63/89 (70.8%)0.025
FDG PET
 Normal0/0 (?)2/15 (13.3%)N/A
 Temporal focus0/0 (?)13/15 (86.7%)N/A
Intracranial electrode implantation6 (54.5%)70 (47.6%)0.692
Surgery
 SAH2 (18.2%)25 (17%)0.839
 ATL7 (63.6%)111 (75.5%)0.417
 ATL and lesionectomy0 (0%)6 (4.1%)1.000
 Lesionectomy2 (18.2%)5 (3.4%)0.039
 ECOG0 (0%)4 (2.7%)0.610
Pathology
 Sclerosis 7 (63.6%)62 (42.2%)0.179
 Cavernoma 1 (9.1%)3 (2%)0.162
 Glioma1 (9.1%)4 (2.7%)0.199
 Ganglioglioma 0 (0%)6 (4.1%)1.000
 Focal cortical dysplasia 0 (0%)4 (2.7%)0.610
 DNET 0 (0%)2 (1.4%)1.000
 Gliosis 0 (0%)3 (2%)0.572
 Normal 0 (0%)24 (16.3%)0.172