Research Article
Antioxidant Capacity, Cytoprotection, and Healing Actions of the Leaf Aqueous Extract of Ocimum suave in Rats Subjected to Chronic and Cold-Restraint Stress Ulcers
Table 3
Healing effect of the leaf aqueous extract of O. suave on chronic acetic acid-induced gastric ulcers in rats.
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: number of rats. Statistically different relative to group 2, . Statistically different relative to group 1, . Healthy control: healthy, nonulcerated control rats. Group 1 (ulcerated rats sacrificed 4 days after acetic acid ulcer induction), showing a deep large ulcer (about 81 mm2), with raised edges and sclerous interior. Group 2 (ulcerated rats given vehicle for 14 days following ulcer induction). Groups 3, 4, and 5 ulcerated rats treated with 125, 250, and 500 mg/kg bw of extract, respectively, for 14 d after day 4 of ulcer establishment. Positive control rat given ranitidine (50 mg/kg bw) for 14 d after ulcer establishment. |