Cardiovascular Psychiatry and Neurology
Volume 2013 (2013), Article ID 159850, 11 pages
Review Article

A Systematic Review of Depression and Anxiety in Patients with Atrial Fibrillation: The Mind-Heart Link

1Mercy Street Vincent's Medical Center, 2213 Cherry St., Toledo, OH 43608, USA
2Electrophysiology and Cardiac Arrhythmias, Dante Pazzanese Institute of Cardiology, 04012-909 SP, Brazil

Received 30 January 2013; Revised 28 March 2013; Accepted 28 March 2013

Academic Editor: Janusz K. Rybakowski

Copyright © 2013 Dimpi Patel et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Atrial fibrillation (AF) is the most commonly seen arrhythmia in clinical practice. At present, few studies have been conducted centering on depression and anxiety in AF patients. Our aim in this systematic review is to use the relevant literature to (1) describe the prevalence of depression and anxiety in AF patients, (2) assess the impact that depression and anxiety have on illness perception in patients with AF, (3) provide evidence to support a hypothetical connection between the pathophysiology of AF and depression and anxiety, (4) evaluate the benefit of treatment of AF on depression and anxiety, and (5) give insight on medically managing a patient with AF and concomitant depression and anxiety.