(a) Schematic of alternative splicing of PKC pre-mRNA generating PKCI mRNA and PKCδVIII mRNA via alternative 5′ splice site selection. E: exon; SS: splice site. (b) Schematic of alternative splicing of Bcl-x pre-mRNA generating Bcl-xL mRNA and Bcl-xS mRNA via alternative 5′ splice site selection. E: exon; SS: splice site. (c) Schematic of alternative splicing of caspase 9 pre-mRNA generating caspase 9a mRNA and caspase 9b mRNA via cassette exon inclusion. (d) Western blot analysis of differentiating lean preadipocytes from days 0 to 10 using antibodies as indicated in the figure. Between days 2 and 4, a marked shift is observed in the splicing pattern of survival proteins. This period marks terminal differentiation of adipocytes. The blots are representative of 3 experiments performed individually with similar results. Graph represents percent PKC exon inclusion calculated as PKCδVIII/(PKCVIII + PKCI) × 100 and is representative of four experiments performed separately.