New Stability Indicating Method for Quantification of Impurities in Amlodipine and Valsartan Tablets by Validated HPLC

<table class="table-group" id="tab4"><tr><td><table class="table"><tr><td class="thead-hr" colspan="5"><hr/></td></tr><tr class="thead"><td align="left">Concentration <br/>µg/mL</td><td align="center">% Spiking level</td><td align="center">Average peak area</td><td align="center">% Recovery</td><td align="center">Mean recovery %</td></tr><tr><td class="thead-hr" colspan="5"><hr/></td></tr><tr><td align="center" colspan="5">Amlodipine imp-A</td></tr><tr><td align="left">0.0310<br/>0.3110<br/>3.1100</td><td align="center">0.05<br/>0.5<br/>2.0</td><td align="center">2806<br/>28745<br/>121197</td><td align="center">94.0<br/>96.3<br/>101.5</td><td align="center">101.5</td></tr><tr><td align="left" colspan="5"><hr/></td></tr><tr><td align="center" colspan="5">Valsartan imp-B</td></tr><tr><td align="left">1.6475<br/>16.475<br/>164.75</td><td align="center">0.05<br/>0.5<br/>1.0</td><td align="center">339061<br/>3398554<br/>6795594</td><td align="center">105.2<br/>105.5<br/>105.4</td><td align="center">105.4</td></tr><tr class="table-tr"><td colspan="5"><hr class="tbody-hr"/></td></tr></table></td></tr></table>

International Scholarly Research Notices

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Table 4

Table 4: New Stability Indicating Method for Quantification of Impurities in Amlodipine and Valsartan Tablets by Validated HPLC 