Opioid Mechanism Involvement in the Synergism Produced by the Combination of Diclofenac and Caffeine in the Formalin Model
Figure 1
The DRC of oral diclofenac (DIC) in doses of 0.316, 1.0, 3.16, 10.0, 31.6, and 56.2 mg/kg and oral caffeine (CAF) in doses of 1, 1.78, and 3.16 mg/kg. For each dose, the mean of 6 determinations ± S.E.M. was plotted on the graph.
