Review Article

Time Course of Placebo Effect of Acupuncture on Pain: A Systematic Review

Table 1

Characteristics of included trials.

StudyClinical conditionsNumber of randomized patients*Allocation concealmentTreatment duration (session)Sham type

Scharf et al. [15]Knee osteoarthritis709 (367, 342)Central randomization6 weeks (10)Superficial needling at nonacupoints
Brinkhaus et al. [16]Low back pain154 (75, 79)Centralized telephone randomization8 weeks (12)Superficial needling at nonacupoints
Witt et al. [17]Knee osteoarthritis150 (76, 74)Centralized telephone randomization8 weeks (12)Superficial needling at nonacupoints
Linde et al. [18]Migraine157 (81, 76)Centralized telephone randomization8 weeks (12)Superficial needling at nonacupoints
Melchart et al. [19]Tension-type headache138 (63, 75)Centralized telephone randomization8 weeks (12)Superficial needling at nonacupoints
Molsberger et al. [20]Low back pain121 (61, 60)Central telephone randomization4 weeks (12)Superficial needling at nonacupoints
Leibing et al. [21]Low back pain100 (50, 50)Unclear12 weeks (20)Superficial needling at nonacupoints
Foster et al. [22]Knee osteoarthritis235 (119, 116)Centralized telephone randomization3 weeks (6)Nonpenetrating needles at acupoints
Cherkin et al. [23]Low back pain323 (162, 161)Central randomization7 weeks (10)Toothpick at acupoints
Kotani et al. [24]Abdominal scar pain46 (23, 23)Sequentially sealed opaque envelopes4 weeks (20)Normal needling at nonpainful points
S. H. Lee and B.C. Lee [25]Prostatitis26 (13, 13)Unclear6 weeks (12)Superficial needling at nonacupoints and mock electrical stimulation
Helms [26]Primary dysmenorrhea22 (11, 11)Unclear12 weeks (9)Normal needling at nonacupoints
Sprott [27]Fibromyalgia20 (10, 10)Unclear3 weeks (6)Disconnected laser instrument
Greco et al. [28]Systemic lupus erythematosus16 (8, 8)Sequentially sealed opaque envelopes5 weeks (10)Superficial needling at nonacupoints
Suarez-Almazor et al. [29]Knee osteoarthritis374 (302, 72)Sequentially sealed opaque envelopes6 weeks (12)Superficial needling at nonacupoints

Values are for total randomized patients (patients in sham and no-treatment groups, resp.).
This trial provided additional sessions for patients who experienced a pain reduction.