Research Article
RP-HPLC Method for Determination of Several NSAIDs and Their Combination Drugs
Table 6
Intraday and interday precision of drugs.
| Drug | Concentration (g/mL) | Intraday | Interday precision () | | | Day 0 () | Day 1 () | Day 2 () | Mean ± SD (g/mL) | RSD (%) | Mean ± SD (g/mL) | RSD (%) | Mean ± SD (g/mL) | RSD (%) | Mean ± SD (g/mL) | RSD (%) |
| PCM | 5 | | 0.90 | | 0.93 | | 0.85 | | 0.96 | 20 | | 0.42 | | 0.72 | | 0.70 | | 0.88 | 40 | | 0.79 | | 0.66 | | 0.75 | | 0.42 |
| THC | 10 | | 0.92 | | 0.59 | | 0.90 | | 0.88 | 40 | | 0.44 | | 0.42 | | 0.25 | | 0.48 | 80 | | 0.31 | | 0.46 | | 0.56 | | 0.24 |
| SA | 10 | | 0.56 | | 0.93 | | 0.68 | | 0.70 | 40 | | 0.51 | | 0.44 | | 0.25 | | 0.38 | 80 | | 0.30 | | 0.33 | | 0.21 | | 0.34 |
| MCX | 10 | | 0.81 | | 0.83 | | 0.81 | | 0.82 | 40 | | 0.67 | | 0.34 | | 0.45 | | 0.50 | 80 | | 0.53 | | 0.32 | | 0.47 | | 0.49 |
| ASP | 10 | | 0.67 | | 0.86 | | 0.83 | | 0.59 | 40 | | 0.49 | | 0.36 | | 0.32 | | 0.42 | 80 | | 0.43 | | 0.44 | | 0.19 | | 0.36 |
| DOM | 10 | | 0.55 | | 0.54 | | 0.61 | | 0.67 | 40 | | 0.63 | | 0.44 | | 0.40 | | 0.38 | 80 | | 0.34 | | 0.25 | | 0.13 | | 0.54 |
| CPM | 10 | | 0.73 | | 0.87 | | 0.61 | | 0.25 | 40 | | 0.32 | | 0.42 | | 0.43 | | 0.51 | 80 | | 0.32 | | 0.31 | | 0.30 | | 0.33 |
| DXM | 20 | | 0.67 | | 0.35 | | 0.29 | | 0.85 | 80 | | 0.27 | | 0.32 | | 0.23 | | 0.17 | 160 | | 0.19 | | 0.33 | | 0.17 | | 0.34 |
| KTL | 10 | | 0.34 | | 0.75 | | 0.91 | | 0.91 | 40 | | 0.41 | | 0.42 | | 0.39 | | 0.39 | 80 | | 0.24 | | 0.58 | | 0.11 | | 0.43 |
| ETC | 10 | | 0.92 | | 0.86 | | 0.65 | | 1.00 | 40 | | 0.61 | | 0.51 | | 0.50 | | 0.62 | 80 | | 0.26 | | 0.58 | | 0.23 | | 0.34 |
| NPX | 5 | | 0.90 | | 0.73 | | 0.90 | | 0.91 | 20 | | 0.85 | | 0.83 | | 0.49 | | 0.89 | 40 | | 0.79 | | 0.65 | | 0.30 | | 0.39 |
| ACF | 10 | | 0.37 | | 0.39 | | 0.73 | | 0.91 | 40 | | 0.41 | | 0.19 | | 0.40 | | 0.44 | 80 | | 0.43 | | 0.34 | | 0.33 | | 0.21 |
| DCF | 10 | | 0.84 | | 0.77 | | 0.83 | | 0.94 | 40 | | 0.16 | | 0.37 | | 0.50 | | 0.69 | 80 | | 0.03 | | 0.50 | | 0.07 | | 0.19 |
| IBF | 20 | | 0.97 | | 0.33 | | 0.75 | | 0.77 | 80 | | 0.40 | | 0.13 | | 0.24 | | 0.27 | 160 | | 0.32 | | 0.27 | | 0.17 | | 0.29 |
| CLP | 10 | | 0.83 | | 1.69 | | 0.70 | | 0.84 | 40 | | 0.49 | | 0.46 | | 0.61 | | 0.40 | 80 | | 0.29 | | 0.93 | | 0.10 | | 0.37 |
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