Research Article
RP-HPLC Method for Determination of Several NSAIDs and Their Combination Drugs
Table 8
Full factorial design of experiments for robustness.
| Exp. | Pattern | Flow rate (mL/min.) | pH | Buffer strength (mM) | Temperature (°C) |
| 1 | | 1.2 | 3.05 | 10 | 30 | 2 | | 1 | 3.05 | 10 | 40 | 3 | | 1.2 | 3.05 | 10 | 40 | 4 | | 1 | 3.05 | 20 | 30 | 5 | | 1 | 3.45 | 20 | 30 | 6 | | 1 | 3.45 | 20 | 40 | 7 | | 1.2 | 3.05 | 20 | 30 | 8 | | 1 | 3.05 | 20 | 40 | 9 | | 1.2 | 3.05 | 20 | 40 | 10 | | 1.2 | 3.45 | 10 | 30 | 11 | | 1 | 3.45 | 10 | 30 | 12 | | 1 | 3.05 | 10 | 30 | 13 | | 1.2 | 3.45 | 10 | 40 | 14 | | 1.2 | 3.45 | 20 | 40 | 15 | | 1 | 3.45 | 10 | 40 | 16 | | 1.2 | 3.45 | 20 | 30 |
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