Eosinophil activity and platelet sequestration in asthmatic airway. TEM of eosinophil shows the peculiar granules with electron dense core surrounded by electron lucent matrix. Asthmatic mice of subacute (a) model show more granules (white arrows) with loss of either core or matrix indicating more degranulation and thus more activation, and in contrast asthmatic mice of chronic (b) model show more intact granules indicating less degranulation and thus less activation. (c) Numerous platelets (pl) are seen in and around the blood vessel in asthmatic mice, and higher magnification (d) shows the process of platelet sequestration (circle), n, nucleus. Images are at 3200X magnification.