Metabolic Bone Disease in Viral Cirrhosis: A Prospective Study
Table 4
Clinical and biological characteristics of patients with normal BMD and those with low BMD.
Criteria
Normal BMD
Low BMD
Age (years)
57.8 ± 9.2
65.5 ± 8.4
0.02
Weight (kg)
71.3 ± 13.6
64.3 ± 8.7
NS
BMI (kg/m2)
26.7 ± 4.2
22.4 ± 1.8
0.01
Liver disease duration
6.6 ± 4.4
10.8 ± 5.3
0.04
Etiology ()
VHC: 7/VHB: 2
VHC: 33/VHB: 4
NS
Child-Pugh score ()
A: 7/B: 2
A: 33/B: 4
NS
Serum bilirubin (mg/L)
8 6–11
8 6–9.6
NS
Alkaline phosphatase (UI/L)
101 ± 34
114.5 ± 48.8
NS
Serum calcium (mg/L)
91.5 ± 4.6
89.3 ± 6.02
NS
Serum phosphorus(mg/L)
34.2 ± 4.8
32.8 ± 5.9
NS
24 h urinary calcium (mg/24 h)
175.2 117–245
86 58.2–181.4
NS
24 h urinary phosphorus (mg/24 h)
774.3 ± 249.9
550 ± 224.1
NS
25 hydroxy-vitamin D (μg/L)
16.8 ± 3.9
12.3 ± 5
0.01
Parathyroid hormon (pg/mL)
46.4 24–116
59 47–102
NS
BMD: bone mineral density; BMI: body mass index; VHB: viral hepatitis B; VHC: viral hepatitis C; NS: nonsignificant. Data are expressed as mean ± standard deviation or median (quartiles).
