International Scholarly Research Notices

Clinical Study

Urea Concentration and Haemodialysis Dose

Table 4

Dialysis with dual targets: minimum stdEKR and maximum TAC.


Label	Variable	Unit	Group 1		Group 2		Group 3		All
Label	Variable	Unit	Mean	SD	Mean	SD	Mean	SD	Mean	SD

	Number of sessions		164		346		109		619
	Postdialysis distribution volume	L	35.1	6.1	30.1	6.1	39.0	6.6	33.0	7.1
	Urea generation rate	μmol/min	138	31	190	39	313	57	198	71
nPCR	Normalised protein catabolic rate	g/kg/day	0.77	0.09	1.14	0.16	1.41	0.23	1.09	0.27
	Renal urea clearance	mL/min	0.49	1.02	0.90	1.37	0.78	1.46	0.77	1.31
	Dialyser urea clearance	mL/min	189	0	189	0	189	0	189	0
	Dialysis frequency	/wk	3.00	0.00	3.00	0.00	5.00	0.00	3.35	0.76
	Dialysis time	min	186	37	215	44	207	34	206	42
	Weekly dialysis time	h	9.3	1.9	10.7	2.2	17.3	2.8	11.5	3.5
wUF	Weekly ultrafiltration volume	L	7.98	2.87	7.81	2.78	10.53	2.70	8.33	2.97
TAC	Time-averaged concentration	mmol/L	14.5	2.2	17.7	0.0	17.7	0.0	16.8	1.8
PAC	Average predialysis concentration	mmol/L	19.2	2.9	25.1	1.4	23.7	1.0	23.3	3.1
std EKR	std EKR	/wk	2.74	0.01	3.64	0.60	4.64	0.86	3.58	0.85
std	std	/wk	2.07	0.07	2.56	0.32	3.44	0.50	2.59	0.55

Note: the predefined treatment parameters and target values are in bold.