Clinical Study
Urea Concentration and Haemodialysis Dose
Table 5
Dialysis with dual targets: minimum std
and maximum PAC.
| Label | Variable | Unit | Group 1 | Group 2 | Group 3 | All | Mean | SD | Mean | SD | Mean | SD | Mean | SD |
| | Number of sessions | | 205 | | 272 | | 142 | | 619 | | | Postdialysis distribution volume | L | 34.7 | 6.3 | 30.1 | 6.1 | 36.1 | 7.9 | 33.0 | 7.1 | | Urea generation rate | μmol/min | 143 | 34 | 191 | 40 | 290 | 66 | 198 | 71 | nPCR | Normalised protein catabolic rate | g/kg/day | 0.80 | 0.10 | 1.14 | 0.13 | 1.41 | 0.21 | 1.09 | 0.27 | | Renal urea clearance | mL/min | 0.54 | 1.06 | 1.01 | 1.44 | 0.66 | 1.33 | 0.77 | 1.31 | | Dialyser urea clearance | mL/min | 189 | 0 | 189 | 0 | 189 | 0 | 189 | 0 | | Dialysis frequency | /wk | 3.00 | 0.00 | 3.00 | 0.00 | 5.00 | 0.00 | 3.46 | 0.84 | | Dialysis time | min | 181 | 44 | 208 | 50 | 177 | 42 | 192 | 48 | | Weekly dialysis time | h | 9.0 | 2.2 | 10.4 | 2.5 | 14.7 | 3.5 | 11.0 | 3.4 | wUF | Weekly ultrafiltration volume | L | 7.99 | 2.87 | 7.82 | 2.86 | 9.80 | 2.83 | 8.33 | 2.97 | TAC | Time-averaged concentration | mmol/L | 15.5 | 2.8 | 18.2 | 1.2 | 19.3 | 0.9 | 17.6 | 2.4 | PAC | Average predialysis concentration | mmol/L | 20.4 | 3.4 | 25.4 | 0.1 | 25.4 | 0.0 | 23.7 | 3.1 | std EKR | std EKR | /wk | 2.70 | 0.12 | 3.58 | 0.65 | 4.28 | 0.95 | 3.45 | 0.86 | std | std | /wk | 2.05 | 0.00 | 2.54 | 0.34 | 3.23 | 0.54 | 2.54 | 0.55 |
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Note: the predefined treatment parameters and target values are in bold.
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