Flow Cytometric Measurement of Aneuploid DNA Content Correlates with High S-Phase Fraction and Poor Prognosis in Patients with Non-Small-Cell Lung Cancer

<table class="table-group" id="tab2"><tr><td><table class="table"><tr><td class="thead-hr" colspan="2"><hr/></td></tr><tr class="thead"><td align="left">Features</td><td align="center">No. (%) (<svg height="11.125" id="M7" style="vertical-align:-0.1638pt" version="1.1" viewbox="0 0 44.400002 11.125" width="44.400002" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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q42 56 97 103.5t96 71.5q46 26 74 26q9 0 16 -2.5t14 -11.5t9.5 -24.5t-1 -44t-13.5 -68.5q-30 -117 -47 -200q-4 -19 -3.5 -25t6.5 -6q21 0 70 48z" id="x1D45B"></path></g><g transform="matrix(.017,-0,0,-.017,13.305,10.862)"><path d="M535 323h-483v50h483v-50zM535 138h-483v50h483v-50z" id="x3D"></path></g><g transform="matrix(.017,-0,0,-.017,28.008,10.862)"><path d="M456 178h-96v-72q0 -51 12.5 -62.5t72.5 -16.5v-27h-256v27q65 5 78 17t13 62v72h-260v28q182 271 300 426h40v-407h96v-47zM280 225v295h-2q-107 -148 -196 -295h198z" id="x34"></path></g><g transform="matrix(.017,-0,0,-.017,36.168,10.862)"><path d="M285 378v-2q65 -13 102 -54.5t37 -97.5q0 -57 -30.5 -104.5t-74 -75t-85.5 -42t-72 -14.5q-31 0 -59.5 11t-40.5 23q-19 18 -16 36q1 16 23 33q13 10 24 0q58 -51 124 -51q55 0 88 40t33 112q0 64 -39 96.5t-88 32.5q-29 0 -64 -11l-6 29q77 25 118 57.5t41 84.5
q0 45 -26.5 69.5t-68.5 24.5q-67 0 -120 -79l-20 20l43 63q51 56 127 56h1q66 0 107 -37t41 -95q0 -42 -31 -71q-22 -23 -68 -54z" id="x33"></path></g>
</svg>)</td></tr><tr><td class="thead-hr" colspan="2"><hr/></td></tr><tr><td align="left">Histopathological type</td><td align="center"> </td></tr><tr><td align="left"> Squamous cell carcinoma</td><td align="center">14 (32.5)</td></tr><tr><td align="left"> Adenocarcinoma</td><td align="center">16 (37.2)</td></tr><tr><td align="left"> Large cell carcinoma</td><td align="center">7 (16.3)</td></tr><tr><td align="left"> Other </td><td align="center">6 (14.0)</td></tr><tr><td align="left">Grade of differentiation</td><td align="center"> </td></tr><tr><td align="left"> Well </td><td align="center">8 (18.6)</td></tr><tr><td align="left"> Moderate</td><td align="center">15 (34.9)</td></tr><tr><td align="left"> Poor</td><td align="center">20 (46.5)</td></tr><tr><td align="left">Degree of cell pleomorphism</td><td align="center"> </td></tr><tr><td align="left"> Low</td><td align="center">17 (39.5)</td></tr><tr><td align="left"> Moderate</td><td align="center">16 (37.2)</td></tr><tr><td align="left"> High</td><td align="center">10 (23.3)</td></tr><tr><td align="left">Necrosis index</td><td align="center"> </td></tr><tr><td align="left"> &lt;50%</td><td align="center">31 (72.1)</td></tr><tr><td align="left"> ≥50%</td><td align="center">12 (27.9)</td></tr><tr class="table-tr"><td colspan="2"><hr class="tbody-hr"/></td></tr></table></td></tr><tr class="table-fn"><td>No.: number of cases; %: percentages.<br/></td></tr></table>

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tab2

Table 2

Table 2: Flow Cytometric Measurement of Aneuploid DNA Content Correlates with High S-Phase Fraction and Poor Prognosis in Patients with Non-Small-Cell Lung Cancer 

Table 2 | Flow Cytometric Measurement of Aneuploid DNA Content Correlates with High S-Phase Fraction and Poor Prognosis in Patients with Non-Small-Cell Lung Cancer 