Research Article

Flow Cytometric Measurement of Aneuploid DNA Content Correlates with High S-Phase Fraction and Poor Prognosis in Patients with Non-Small-Cell Lung Cancer

Table 3

Distribution of S-phase fraction and proliferation index according to DNA content status.

FactorAll patients
( )
Diploid
( )
Aneuploid
( )
P value

S-phase fraction (SPF)0.0022
 Low23176
 High20515

Proliferation index0.0040
 Low16133
 High27918

SFS: cell in S-phase of cell cycle, proliferation index: cells in both S and G2/M phases of cell cycle, low: less than 25% of proliferating cells, high: more than 25%.