Research Article

Lomustine Analogous Drug Structures for Intervention of Brain and Spinal Cord Tumors: The Benefit of In Silico Substructure Search and Analysis

Table 3

Log BB and BB values.

AgentLog BBBB

1, lomustine 0.473
2 0.361
3 0.372
4 0.342
5 0.396
6 0.414
7 0.335
8 0.372
9 0.393
10 0.383
11 0.399
12 0.144
13 0.512
14 0.402
15 0.422
16 0.662
17 0.511
18 0.397