Comparative Effects of Phosphoenolpyruvate, a Glycolytic Intermediate, as an Organ Preservation Agent with Glucose and N-Acetylcysteine against Organ Damage during Cold Storage of Mouse Liver and Kidney
Figure 3
Effects of PEP on mouse kidney damage during cold preservation. (a) Changes in LDH concentrations in the preservation solutions; PBS , PBS + 1 mM PEP , + 10 mM PEP , and + 100 mM PEP . Each bar represents the mean SEM. * and **, compared with the PBS group. (b) Histological pictures of the kidney 72 h after cold preservation. The liver tissues were fixed with 10% buffered formalin, embedded in paraffin, sectioned, and stained with hematoxylin-eosin. Nonpreserved fresh kidney served as a control. Scale bar μm.