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Chromatography Research International
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Special Issues
Chromatography Research International
/
2013
/
Article
/
Tab 4
/
Research Article
Development and Validation of an RP-HPLC Method for Estimation of Chlorpheniramine Maleate, Ibuprofen, and Phenylephrine Hydrochloride in Combined Pharmaceutical Dosage Form
Table 4
Solvent stability study.
Time
(Hrs.)
Area (
)
Result %
CPM
2 (
μ
g/mL)
IBU
100 (
μ
g/mL)
PHE
5 (
μ
g/mL)
CPM
IBU
PHE
0
61521
4158429
124685
100
100
100
3
61009
4146734
123619
99.16
99.14
99.14
6
60913
4116520
121706
99.01
98.99
97.61
24
60157
4104629
120648
98.71
98.70
96.76