Review Article
UGT2B17 Polymorphism and Risk of Prostate Cancer: A Meta-Analysis
Table 1
Characteristics of studies included in the meta-analysis.
| First author | Year | Country | Ethnicity | Samples size (case/control) | OR (95% CI) | Source of controls | Genotyping methodc |
|
Setlur [23] | 2010 | Austria | Caucasians | 121/205 | 0.88 (0.45–1.73)a | Hospital based | PCR | Karypidis [24] | 2008 | Sweden | Caucasians | 174/161 | 2.07 (1.32–3.25)a | Hospital based | RT PCR | Olsson et al. [25] | 2008 | Sweden | Caucasians | 2,480/1,672 | 1.01 (0.83–1.23)b | Population based | Multiplex PCR |
Park [26] | 2007 | USA | Whites | 247/273 | 1.7 (1.03–2.9)a | Hospital based | PCR-RFLP |
Gallagher [27] | 2007 | USA | Caucasians | 411/397 | 0.97 (0.73–1.30)a | Hospital based | RT PCR |
Park [28] | 2006 | USA | Caucasian | 293/367 | 1.9 (1.2–3.0)a |
Hospital based |
RT PCR | African Americans | 113/115 | 1.3 (0.6–2.7)a |
|
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Adjusted odds ratio (OR) and 95% confidence interval (CI). Unadjusted odds ratio (OR) and 95% confidence interval (CI). Genotyping method—PCR: polymerase chain reaction, RT-PCR: real-time polymerase chain reaction, and PCR-RFLP: polymerase chain reaction-restriction fragment length polymorphism.
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