Research Article

In Vivo and In Vitro Antidiabetic Activity of Terminalia paniculata Bark: An Evaluation of Possible Phytoconstituents and Mechanisms for Blood Glucose Control in Diabetes

Table 1

Blood glucose lowering effect of AETPB in type 2 diabetic rats.

GroupsDose (mg/kg)Blood glucose (mg/dL)
Before diabetes induction (0 day)After diabetes induction (14 days)Day 14Day 28

ControlVehicle
Diabetic controlVehicle
AETPB100
AETPB200
Glibenclamide5

All data are expressed as mean ± SEM ( ). Vehicle: 0.2% CMC (5 mL/kg).
P < 0.001 diabetic control compared with control.
P < 0.001 AETPB 100, 200 mg/kg and glibenclamide 5 mg/kg compared with diabetic control.
P < 0.001 AETPB 200 mg/kg or glibenclamide 5 mg/kg compared with AETPB 100 mg/kg.