Clinical Study

Dual Antiplatelet Therapy Can Be Discontinued at Three Months after Implantation of Zotarolimus-Eluting Stent in Patients with Coronary Artery Disease

Table 2

Lesion characteristics and coronary angiographic outcomes at baseline, immediately after and at 8 months after implantation of the endeavor zotarolimus-eluting stent in the 3- and 12-month DAPT groups.

3-month DAPT
(88 lesions)
12-month DAPT
(81 lesions)
-value

Baseline
 RCA, n (%)36 (40.5)28 (34.6)
 LAD, n (%)33 (37.5)29 (35.8)NS
 LCX, n (%)15 (17.1)18 (22.2)
 LMT, n (%)4 (4.9)6 (7.4)NS
 AHA/ACC Type B1, n (%)22 (24.7)26 (32.0)
 Type B2, n (%)54 (61.6)43 (53.0)NS
 Type C, n (%)5 (5.7)3 (3.7)
 De novo, n (%) 86 (97.7)79 (97.5)NS
 In-stent restenosis, n (%)2 (2.3)2 (2.5)NS
 Bifurcation lesion, n (%)6 (6.8)7 (8.6)NS
 Multivessel disease, n (%)18 (20.5)20 (24.7)NS
 Lesion length, mm13.3 ± 7.0415.6 ± 5.820.02
 RVD, mm2.78 ± 0.522.74 ± 0.53NS
 MLD, mm0.69 ± 0.430.71 ± 0.39NS
 %DS, %73.9 ± 17.373.2 ± 14.9NS
Immediately afterprocedure
 Multiple stenting, n (%)19 (21.5)15 (18.5)NS
 Number of stents per patient1.7 ± 1.11.8 ± 0.7NS
 MLD, mm2.39 ± 0.562.51 ± 0.61NS
 %DS, %9.07 ± 7.567.94 ± 6.69NS
8 months afterprocedure
 RVD, mm2.38 ± 0.532.64 ± 0.51NS
 MLD, mm2.24 ± 0.582.16 ± 0.79NS
 %DS, %19.7 ± 17.321.4 ± 20.2NS
 Late lumen loss, mm0.45 ± 0.520.51 ± 0.47NS
 Binary restenosis, n (%)8 (9.1)9 (11.1)NS

RCA: right coronary artery; LAD: left coronary artery; LCX: left circumflex artery; RVD: reference vessel diameter; MLD: minimal lumen diameter; TLR: target lesion revascularization; TVR: target vessel revascularization; LMT: left main trunk; DAPT: dual antiplatelet therapy; DS: diameter stenosis; NS: not significant.