Review Article

Pharmacotherapy of Chronic Obstructive Pulmonary Disease: A Clinical Review

Table 4

Mode of administration, chemical structure, lipophilicity ( ), and half time ( ) of glucocorticosteroids.

CompoundMode of administrationChemical structure

Fluticasone propionateInhalation (MDI, DPI)582807.tab.004a3.410 hours
BudesonideInhalation (DPI, solution)582807.tab.004b1.92.0–3.6 hours
BeclomethasoneInhalation (MDI, DPI, and solution)582807.tab.004c1.32.8 hours
FlunisolideInhalation (MDI, DPI, and solution)582807.tab.004d1.11.8 hours
Mometasone furoateInhalation (MDI, DPI, and solution)582807.tab.004e2.15.8 hours
TriamcinoloneInhalation (MDI, DPI, and solution)582807.tab.004f0.288 minutes

MDI: metered-dose inhaler, DPI: dry power inhaler.