Hemin and Zinc Protoporphyrin IX Affect Granisetron Constipating Effects In Vitro and In Vivo

<table>Typical tracings of duodenal longitudinal smooth muscle spontaneous basal activity and inhibitory responses to electrical field stimulation (EFS) (10 Hz; 20 V, 1 msec, pulse trains lasting 30 sec) in control rats.</table>

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Figure 1: Hemin and Zinc Protoporphyrin IX Affect Granisetron Constipating Effects In Vitro and In Vivo 