Identification of Functional Regulatory Residues of the β-Lactam Inducible Penicillin Binding Protein in Methicillin-Resistant Staphylococcus aureus
Table 2
Physicochemical properties of PBP-2′ computed using ProtParam server.
ProtParam parameters*
Values
No. of amino acids
670
Molecular weight
76463.2 Da
Theoretical pI
9.09
No. of negative charge residues
90
No. of positive charge residues
105
Formula
C3415H5428N912O1039S18
Extinction coefficient
93630 M−1 cm−1
Estimated half-life
30 hours
Instability index
30.08
Aliphatic index
82.76
Grand average of hydropathicity (GRAVY)
−0.698
Total number of atoms
10812
The physicochemical parameters define the protein chemical and physical properties in its native state. The protein has a net positive charge and is basic in nature ().
