Research Article
Synthesis and Evaluation of Substituted 4,4a-Dihydro-3H,10H-pyrano[4,3-b][1]benzopyran-10-one as Antimicrobial Agent
Table 2
MIC (µg/mL) of compounds 7a–t against different bacterial strains.
| | Comp. number | B. subtilis | S. aureus | E. coli | P. aeruginosa | S. typhi |
| | 7a | — | — | 12.5 | 25 | — | | 7b | — | 12.5 | — | — | — | | 7c | 12.5 | 12.5 | 25 | — | — | | 7d | 1.82 | 1.82 | 1.56 | 12.5 | 12.5 | | 7e | 6.25 | 12.5 | 3.12 | 12.5 | — | | 7f | 12.5 | 25 | 25 | — | — | | 7g | 15.5 | — | — | 12.5 | — | | 7h | 12.5 | 32.5 | — | — | — | | 7i | 1.12 | 0.48 | 0.48 | 1.12 | 25 | | 7j | 25 | 12.5 | 6.25 | 12.5 | — | | 7k | — | 15.5 | 13.3 | — | 25 | | 7l | 25 | 12.5 | 25 | — | — | | 7m | 12.5 | 6.25 | 25 | 25 | — | | 7n | 6.25 | 12.5 | 12.5 | 25 | — | | 7o | 25 | 12.5 | 12.5 | — | 50 | | 7p | — | 15.5 | — | 30.5 | — | | 7q | 12.5 | 6.25 | 25 | 12.5 | 25 | | 7r | — | 25.5 | — | — | — | | 7s | — | 25 | — | — | — | | 7t | 12.5 | — | 30.5 | — | — | | Amoxicillin | 0.5 | 0.5 | 0.12 | 1.0 | 0.9 | | Ciprofloxacin | 0.75 | 1.2 | 0.9 | 1.8 | — |
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