Research Article
Synthesis and Evaluation of Substituted 4,4a-Dihydro-3H,10H-pyrano[4,3-b][1]benzopyran-10-one as Antimicrobial Agent
Table 4
MIC (µg/mL) of compounds 7a–t against different fungal strains.
| | Compound no. | A. niger | S. cerevisiae | C. albicans | C. gastricus | M. gypseum |
| | 7a | 55.4 | 31.5 | >100 | >100 | 88.4 | | 7b | 30 | 14.1 | 65.3 | >100 | >100 | | 7c | 25.2 | 18.6 | 32.5 | >100 | >100 | | 7d | 12.4 | >100 | 70 | 48.5 | 90.2 | | 7e | 19.5 | 30.5 | 16.5 | 75.4 | >100 | | 7f | 28.2 | 18.2 | 11.8 | 80.4 | 94 | | 7g | 13.8 | 32.1 | 55.5 | >100 | 55.4 | | 7h | 2.4 | 11.7 | 16.6 | >100 | 48.5 | | 7i | 16.6 | 10.5 | 17.8 | 58.4 | >100 | | 7j | 11.2 | 2.9 | 61.2 | >100 | 88.5 | | 7k | 29.9 | 71.4 | 54.5 | >100 | >100 | | 7l | 73.5 | 56.4 | 72.4 | >100 | >100 | | 7m | 13.2 | 40.5 | 76 | >100 | 53.4 | | 7n | 34 | >100 | 14.7 | 32.5 | >100 | | 7o | 18.5 | 21.4 | 20.5 | >100 | 93 | | 7p | 35 | 20 | >100 | 43.5 | >100 | | 7q | 21.0 | 32.1 | >100 | 20.5 | 31.5 | | 7r | 15.3 | >100 | 12.4 | >100 | 53 | | 7s | 45.4 | 20 | >100 | 63.5 | >100 | | 7t | 21.0 | 12.1 | >100 | 40.5 | >100 | | Fluconazole | 1.9 | 1.9 | 3.9 | 31.2 | 1.9 |
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