Review Article
A Review of the Clinical Outcomes for Patients Diagnosed with Brainstem Metastasis and Treated with Stereotactic Radiosurgery
Table 1
Collected experience of stereotactic radiosurgery for brainstem metastasis.
| | Study | Year | Method | No. of patients/
No. of lesions | Mean KPS | Median age (yr) | Single BSM* | No. of patients with WBRT | Mean tumor volume (cm3) | Mean follow-up (mo) | Median survival
(mo) | Mean marginal dose
(Gy) | Crude local control (%) |
| | Yoo et al. [4] | 2011 | GK | 32/NR | NR | 56 | 6/19% | NR | 1.5 | 12.0 | 7.7 | 15.9 | 87 | | Valery et al. [11] | 2011 | LINAC | 30/43 | 80 | 57 | 20/67% | 8/27% | 2.8 | 11.0 | 10.0 | 13.4 | 90 | | Hatiboglu et al. [1] | 2011 | LINAC | 60/NR | 90 | 61 | NR | 15/25% | 1.0 | 12.8 | 4.2 | 15.0 | 76 | | Kelly et al. [12] | 2011 | LINAC | 24/NR | 80 | 57 | 3/13% | 23/96% | 0.2 | 6.6 | 5.3 | 13.0 | 79 | | Koyfman et al. [5] | 2010 | GK | 43/43 | 80 | 59 | 43/100% | 34/79% | 0.37 | 5.3 | 5.8 | 15.0 | 85 | | Lorenzoni et al. [13] | 2009 | GK | 25/27 | 79 | 53 | 6/24% | 17/68% | 0.60 | 5.2 | 11.1 | 20.0 | 95 | | Kased et al. [14] | 2008 | GK | 42/44 | 90 | 55 | 5/12% | 24/57% | 0.26 | 6.9 | 9.0 | 16.0 | 85 | | Hussain et al. [8] | 2007 | GK | 22/25 | 92 | 60 | 19/86% | 3/14% | 0.90 | 8.5 | 8.5 | 16.0 | 100 | | Fuentes et al. [15] | 2006 | GK | 28/NR | 80 | 58 | 20/71% | 6/21% | 2.1 | 11.0 | 12.0 | 19.6 | 92 | | Yen et al. [10] | 2006 | GK | 53/NR | 80 | 57 | 19/36% | 21/40% | 2.8 | 9.8 | 11.0 | 17.6 | NR | | Shuto et al. [9] | 2003 | GK | 25/31 | NR | 54 | 8/32% | 7/28% | 2.1 | 5.2 | 4.9 | 13.0 | 77 | | Huang et al. [7] | 1999 | GK | 26/27 | 80 | 61 | 11/42% | 24/92% | 2.0 | 9.5 | 9.0 | 16.0 | 95 |
|
|
GK: Gamma Knife, LINAC: linear accelerator, NR: not reported
= median, = mean.
|
