Research Article
Formulation Development and Evaluation of Fast Disintegrating Tablets of Salbutamol Sulphate for Respiratory Disorders
Table 5
Evaluation parameters for the optimization of sodium starch glycolate.
| Sr. no. | Evaluation parameters | F1 (1%) | F2 (2%) | F3 (4%) | F4 (6%) | F5 (8%) | F6 (10%) |
| 1 | Weight variation (IP) | Passed | Passed | Passed | Passed | Passed | Passed | 2 | Friability (%) | 0.8 | 0.8 | 0.1 | 0.3 | 0.1 | 0.1 | 3 |
*Hardness (Kg/cm2) ± S.D | 2.2 ± 0.57 | 1.6 ± 0.28 | 1.5 ± 0.28 | 1.5 ± 0.32 | 2.0 ± 0.57 | 1.8 ± 0.28 | 4 |
**Disintegration time (sec) ± S.D | 80 ± 2.34 | 59 ± 6.67 | 34 ± 2.63 | 48 ± 6.38 | 78 ± 7.39 | 95 ± 6.97 |
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Average of three determinations.
**Average of six determinations.
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