Formulation Development and Evaluation of Fast Disintegrating Tablets of Salbutamol Sulphate for Respiratory Disorders

<table class="table-group" id="tab7"><tr><td><table class="table"><tr><td class="thead-hr" colspan="3"><hr/></td></tr><tr class="thead"><td align="left">Sr. no.</td><td align="center">Evaluation parameters</td><td align="center">Results</td></tr><tr><td class="thead-hr" colspan="3"><hr/></td></tr><tr><td align="left">1</td><td align="center">Weight variation (IP)</td><td align="center">Passed</td></tr><tr><td align="left">2</td><td align="center">
                  *Thickness (mm) ± S.D</td><td align="center">3.63 ± 0.06</td></tr><tr><td align="left">3</td><td align="center">
                  *Hardness (Kg/cm<sup>2</sup>) ± S.D</td><td align="center">1.5 ± 0.29</td></tr><tr><td align="left">4</td><td align="center">Friability (%)</td><td align="center">0.5</td></tr><tr><td align="left">5</td><td align="center">
                  **Disintegration time (sec) ± S.D</td><td align="center">45 ± 2.34</td></tr><tr><td align="left">6</td><td align="center">
                  *Wetting time (sec) ± S.D</td><td align="center">28 ± 1.53</td></tr><tr><td align="left">7</td><td align="center">
                  *Drug content uniformity (mg)</td><td align="center"> 103.6 ± 3.36 </td></tr><tr class="table-tr"><td colspan="3"><hr class="tbody-hr"/></td></tr></table></td></tr><tr class="table-fn"><td><svg height="13.75" id="M6" style="vertical-align:-0.0pt" version="1.1" viewbox="0 0 7.7375002 13.75" width="7.7375002" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
<g transform="matrix(.012,-0,0,-.012,.062,5.525)"><path d="M471 153q-22 -15 -61 -13q-25 31 -45.5 49.5t-56.5 41.5q4 -71 28 -134q-17 -33 -42 -46q-24 12 -42 46q24 63 28 134q-36 -23 -56.5 -41.5t-45.5 -49.5q-36 -2 -61 13q0 28 19 59q65 10 130 43q-65 33 -130 43q-19 31 -19 59q22 15 61 13q25 -31 45.5 -49.5t56.5 -41.5
q-4 71 -28 134q17 33 42 46q24 -12 42 -46q-24 -63 -28 -134q36 23 56.5 41.5t45.5 49.5q36 2 61 -13q0 -28 -19 -59q-65 -10 -130 -43q65 -33 130 -43q19 -31 19 -59z" id="x2217"></path></g>
</svg>Average of three determinations.<br/>
                **Average of six determinations.<br/></td></tr></table>

Official tests for salbutamol sulphate FDT.

International Scholarly Research Notices

tab7

Table 7

Table 7: Formulation Development and Evaluation of Fast Disintegrating Tablets of Salbutamol Sulphate for Respiratory Disorders 