Research Article
Loss of Villin Immunoexpression in Colorectal Carcinoma Is Associated with Poor Differentiation and Survival
Table 4
Distribution of villin-positive immunoexpression in relation to clinicopathological characteristics.
| | | Number (%) | Mean (SEM) | value |
| | Age | | | | | >60 years | 38/45 (84.4%) | 16.24 (2.13) | 0.558 | | ≥60 years | 41/48 (85.4%) | 18.33 (2.16) | | Sex | | | | | Male | 35/44 (79.5%) | 15.8 (2.26) | 0.270 | | Female | 44/49 (89.8%) | 18.69 (2.04) | | Tumour location | | | | | Right colon | 25/30 (83.3%) | 17.6 (2.33) | 0.891* | | Left colon | 21/26 (80.8%) | 16.69 (3.16) | | Rectum | 34/37 (91.9%) | 17.54 (2.51) | | Tumour size | | | | | <5 cm | 27/29 (93.1%) | 20.21 (2.96) | 0.042 | | ≥5 cm | 17/24 (70.8%) | 12.42 (2.38) | | Primary tumour | | | | | T2 | 10/12 (83.3%) | 14.33 (4.303) | 0.120* | | T3 | 9/10 (90%) | 24.3 (4.41) | | T4 | 25/31 (80.6%) | 15.129 (2.56) | | Tumour grade | | | | | Well differentiated | 22/25 (88%) | 20.20 (14.99) | 0.035* | | Moderately differentiated | 52/63 (82.5%) | 16.95 (14.39) | | Poorly differentiated | 3/5 (60%) | 3.6 (4.62) | | Nodal metastasis | | | | | Positive | 24/31 (77.4%) | 14.19 (13.11) | 0.229 | | Negative | 22/24 (91.7%) | 18.63 (15.46) | | Lymphovascular invasion | | | | | Positive | 6/7 (85.7%) | 12.29 (3.39) | 0.729 | | Negative | 38/46 (82.6%) | 16.913 (2.22) | | Margin status | | | | | Involved | 4/6 (66.7%) | 20.33 (7.63) | 0.651 | | Free | 40/47 (85.1%) | 15.79 (2.04) | | Recurrence | | | | | Recurrence | 27/30 (90%) | 19.36 (2.6) | 0.474 | | No recurrence | 29/33 (87.9%) | 16.8 (2.58) | | Status at end point | | | | | Died of disease | 21/23 (91.3%) | 18.22 (3.11) | 0.748 | | Alive | 58/70 (82.6%) | 16.74 (1.74) |
|
|
The Mann-Whitney test; *The Kruskal-Wallis test; SEM: standard error of the mean.
|
