Clinical Study

Effect of Two Different Doses of Gabapentin on the Intraocular Pressure and Hemodynamic Stress Responses to Laryngoscopy and Tracheal Intubation

Table 2

HR (beat/min.) at various intervals.

Control group I (no. 20)Gaptin 800 group II (no. 20)Gaptin 1200 group III (no. 20)

Baseline 81.250 ± 11.6981.05 ± 10.5183.0 ± 12.630.170.84
After induction77.20 ± 10.43*76.10 ± 8.93**76.4 ± 11.51**0.060.94
After intubation93.30 ± 12.48#**83.20 ± 8.980.8 ± 11.39**6.460.002
5 min89.40 ± 11.53#*80.5 ± 8.8577.10 ± 11.63**6.720.002
10 min86.55 ± 10.79#80.2 ± 9.2374.95 ± 11.14**6.210.003

0.0000.0000.000

Data were expressed as mean ± SD.
#Means that control group was significantly different from both groups ( ).
@Means that gabapentin 800 group was significantly different from gabapentin 1200 group ( ).
*Means significant difference from baseline value ( ).
**Means highly significant difference from baseline value ( ).