International Scholarly Research Notices

Research Article

MHC Disparate Resting B Cells Are Tolerogenic in the Absence of Alloantigen-Expressing Dendritic Cells

Table 1

Effects of number of dendritic cells (DCs) on priming versus hyporesponsivenessa.
Dendritic cell dosePercentage of infused cellsGraft survival (days)MST (days)
18, 8, 98
0.58, 9, 99
0.018, 9, 149
0.00513, 17, 2317
0.000121, 22, 2222
0020, 20, 2120
Graded numbers of MHC- DCs were added to purified CD2- B cells and infused into naive FVB mice. After 2 weeks, mice were engrafted with MHC- tail skin grafts and monitored daily for rejection.