Clinical Study
Phase II Study of Bortezomib as a Single Agent in Patients with Previously Untreated or Relapsed/Refractory Acute Myeloid Leukemia Ineligible for Intensive Therapy
Table 3
The extent of antileukemic effect induced by bortezomib is reported for peripheral blood and bone marrow of 13 evaluable patients affected with acute myeloid leukemia. Comparison was performed between baseline values and the time when the maximum effect was recorded.
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Abbreviations: PB: peripheral blood; BM: bone marrow; ANC: absolute neutrophil count; n.v.: not evaluable; ↓PB: decrease in PB blast count; ↓BM: decrease in BM blast count. 1In brackets, PB and/or BM blast reduction is reported as percentage difference compared to the baseline evaluation. |