Research Article

Effect of L. usitatissimum (Flaxseed/Linseed) Fixed Oil against Distinct Phases of Inflammation

Table 1

Effect of L. usitatissimum fixed oil and aspirin on acetic acid induced peritoneal inflammation and peritoneal capillary permeability in mice.

Serial numberTreatmentDoseTotal amount of protein (mg/mL) exudation
3 h after acetic acid administration
(0.25 mL of 1.2%, i.p.)
Absorbance at 625 nm

1Control (distilled water)3 mL/kg5.01 ± 0.210.49 ± 0.02
2L. usitatissimum fixed oil1 mL/kg4.15 ± 0.24* (17.17)0.39 ± 0.05* (20.41)
3L. usitatissimum fixed oil2 mL/kg2.82 ± 0.21* (43.71)0.31 ± 0.03* (36.73)
4L. usitatissimum fixed oil3 mL/kg1.59 ± 0.18* (68.26)0.19 ± 0.05* (61.22)
5Aspirin100 mg/kg1.57 ± 0.16* (68.66)0.20 ± 0.03* (59.18)

Values in parenthesis represent percentage inhibition (values are mean ± SEM).
Each group contains six animals; all groups were compared to the group 1 by Dunnett’s test ( ).