Review Article

Meta-Analysis of the Hemodynamic Properties of Antihypertensive Medications

Table 3

Mean changes in hemodynamic variables with confidence intervals.

Change in MAP with CI (mmHg)Change in HR with CI Change in PV with CI (mL)Change in CO with CI (lit/min) Change in SV with CI (mL/stroke)

ACEIs−16 (−24 to −9)#0.8 (−0.4 to 2) 44 (0.3 to 88)* 0.10 (−0.22 to 0.44)2 (−3 to 7)
-blockers−14 (−16 to −13)#−12 (−14 to −10)#57 (−23 to 140)−0.65 (−0.86 to −0.43)#4 (3 to 6)#
CCBs−15 (−18 to −13)#0.4 (−2 to 3) 59 (−16 to 130) 0.14 (−0.10 to 0.33) 4 (1 to 7)**
Thiazides −12 (−17 to −7)# 0 (−2 to 2)−110 (−290 to 57)−0.63 (−0.75 to −0.51)**−8 (−11 to −5)**

.
** .
# .