Inhibition of CYP1A2-mediated phenacetin O-deethylation (a), CYP2D6-mediated bufurarol 1-hydroxylation (b), and CYP3A-mediated midazolam 1′- (c) and 4′-hydroxylation (d) by atypical antipsychotics. Drugs depicted are clozapine (♦), olanzapine (●), iloperidone (+), quetiapine (○), haloperidol (), chlorpromazine (x), levomepromazine (▲), thioridazine (□), risperidone (■), and abaperidone (◊). Dotted line denotes the corresponding prototypic ihhibitor.