Review Article
The Intrauterine Device in Women with Diabetes Mellitus Type I and II: A Systematic Review
Table 1
Pregnancy rates in diabetic women using the IUD.
| | Study | Subjects | Type of IUD | Type of diabetes (DM1or DM2) (IDDM or NIDDM) | Pregnancy rate at 1 year | Final pregnancy rate (end of study) | Comments |
| | Wiese [5] | 118 | Antigon I, II, III, IV, F | IDDM | |
(24 months) | High removal and expulsion rate, similar in normal subjects | | Buchsenschutz [24] and Serfaty [25] | 56 | CuT200, Cu-7, MLCu250 | IDDM and NIDDM | 0 | 1.7%
(36 months) | Noncumulative pregnancy rate, salpingitis 3.6% and expulsion 10.1% | | Gosden et al. [7] | 30 | Cu-7, Saf-T-Coil, Dalkon Shield | IDDM | 46% | 46%
(12 months) | Abnormal chloride and sulphur deposits on the copper devices | | Skouby et al. [26] | 103 | CuT200 | IDDM | |
(12 months) | Corrosion surfaces of copper-no differences between diabetic and non-diabetic controls | | Kimmerle et al. [27] | 59 | Cu-Safe300 (Flexi-T300) | DM1 | |
(36 months) | Same rate as controls, 78% nulliparous, average HbA1c 7% | | Kimmerle et al. [28] | 127 | Copper IUDs-not specified | DM1 | Not available |
(60 months) | Retrospective study, 70% nulliparous, average HbA1c %, controlled | | Kjos et al. [29] | 117 | TCu380A | DM2 | 0.9 |
(36 months) | 100% multiparous, open study |
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IDDM: insulin dependent diabetes mellitus; NIDDM: non-insulin dependent diabetes mellitus; DM1: diabetes mellitus type I; DM2: diabetes mellitus type II; life table data; Pearl Index; HbA1c: glycosylated haemoglobin.
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