Review Article
The Intrauterine Device in Women with Diabetes Mellitus Type I and II: A Systematic Review
Table 2
Laboratory values in diabetic women using the IUD.
| | Type of diabetes | Reference | Subjects () | IUD type | Mean initial and concluding values (12 months) | Comments | | HbA1c (%) | IR (U) | FBG |
| | DM1 | Grigoryan et al. [30] | 11 | TCu380A | 7.8-7.8 |
64.5-64.6◊ | | Perimenopausal subjects, no lipid or coagulability changes versus COC; TCu380A was control | | Grigoryan et al. [30] | 11 | LNG-IUS | 7.6-7.7 | | Diab and Zaki [31] | 15 | Tcu380A | | | 109–99∙ | No lipid or coagulability changes versus Norplant, COC and DMPA; TCu380A was control | | Rogovskaya et al. [32] | 29 | LNG-IUS | 5.6–6.3 | 35.2-35.1 | 5.2–7.4o | No changes in HbA1c and FBG for both IUDs. The TCu380A acted as control. There were no pregnancies. | | Rogovskaya et al. [32] | 30 | TCu380A | 5.5–6.3 | 37.3–37.1 | 5.0–7.5o |
| | DM2 | Grigoryan et al. [30] | 11 | TCu380A | 7.5-7.4 | | |
Four perimenopausal DM2 on insulin. No laboratory changes as for DM1 | | Grigoryan et al. [30] | 11 | LNG-IUS | 7.4–7.6 | | Diab and Zaki [31] | 5 | TCu380A | | | 109–99∙ | |
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HbA1c: glycosalated haemoglobin; FBG: fasting blood glucose; IR (U): insulin requirement (international units); COC: combined oral contraceptive; DMPA: depomedroxyprogesterone acetate; ∙mg/dL; ommol/L; ◊pooled values TCu380A and LNG-IUS; †Initial value for DM1 and DM2 (16 subjects).
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