Research Article

Safety Evaluation of Engineered Nanomaterials for Health Risk Assessment: An Experimental Tiered Testing Approach Using Pristine and Functionalized Carbon Nanotubes

Figure 6

Histograms showing changes in percentage of (a) PCNA and (b) TUNEL Labelling Index of bronchiolar, alveolar and macrophagic cells after i.t. exposure to different CNTs (pristine MWCNTs versus lab-made functionalized MW-COOH and MW-NH2). A significant increase (Student’s -test) of the above-mentioned cell types was clearly observed in lungs from all CNT-treated rats. Data are expressed as mean S.D. ( ).
825427.fig.006a
(a)
825427.fig.006b
(b)