Research Article

Ischemia Induces Release of Endogenous Amino Acids from the Cerebral Cortex and Cerebellum of Developing and Adult Mice

Figure 6

Time course of basal (- -) and K+-evoked (- -) glutamate release from cerebellar slices in normoxia and basal (-∆-) and K+-stimulated (-▴-) glycine release in ischemia in 7-day-old (a) and 3-month-old (b) mice. Note the fourfold differences in the scale of the -axis in panels (a) and (b). The results are means of 4–8 independent experiments with SEMs indicated. Ischemia significantly ( ) enhanced the release in both age groups, but K+ stimulation was effective only in ischemia in 7-day-old mice and in normoxia in 3-month-old mice.
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(a)
839036.fig.006b
(b)