Research Article

Early Endoscopy Can Shorten the Duration of Hospitalization in Suspected Variceal Hemorrhage

Table 1

Baseline characteristics of patients in the early and delayed endoscopy groups (suspected variceal hemorrhage).

All patients ( )Early endoscopy ( )Delayed endoscopy ( ) value

Men1135 (37.7%)814 (77.6%)321 (81.7%)0.0918
Age (year)57.0 (13.3)57.1 (13.4)56.6 (13.0)0.4887
Initial symptoms
 Red blood emesis707 (49.03%)540 (51.48%)167 (42.49%)0.0034
 Coffee grounds177 (12.27%)126 (12.01%)51 (12.98%)
 Hematochezia33 (2.29%)20 (1.91%)13 (3.31%)
 Melena453 (31.41%)321 (30.60%)132 (33.59%)
 Others72 (4.99%)42 (4.00%)30 (7.63%)
Mean arterial pressure (mmHg)87.0 (19.9)86.5 (20.1)88.5 (19.2)0.0724
Heart rates (beats/min)103.7 (21.8)104.3 (22.1)102.1 (21.0)0.0790
Respiratory rates (/minutes)17.2 (3.1)17.4 (3.0)16.8 (3.2)0.0027
Body temperature (°C)36.6 (0.8)36.5 (0.8)36.7 (0.9)0.0022
Child’s classification
 A408 (28.29%)301 (28.69%)107 (27.23%)0.0732
 B659 (45.70%)492 (46.90%)167 (42.49%)
 C375 (26.01%)256 (24.40%)119 (30.28%)
Time to endoscopy (hour)9.1 (10.7)4.6 (2.9)20.9 (14.2)<0.0001
Antibiotics use at ED
 Yes138 (9.57%)89 (8.48%)49 (12.7%)0.0220
 No1304 (90.49%)960 (91.52%)344 (87.53%)
Hemoglobin (g/dL)9.2 (2.4)9.2 (2.5)9.3 (2.4)0.3914
White blood cells counts ( /uL)9.68 (6.6)9.89 (7.1)9.13 (4.9)0.0226
Platelet counts ( /uL)127 (82.3)127 (80.2)127 (87.5)0.9998
PTT (seconds)30.8 (8.8)30.7 (8.9)31.1 (8.5)0.5080
Sodium (mmol/L)134.9 (5.4)135.2 (5.3)134.1 (5.6)0.0007
Potassium (mmol/L)4.2 (0.76)4.2 (0.75)4.1 (0.80)0.1071
BUN (mg/dL)32 (21.3)33 (21.4)31 (20.9)0.2806
Creatinine (mg/dL)1.4 (1.3)1.4 (1.4)1.4 (1.2)0.9169
Glucose (mg/dL)173 (100.1)171 (92.3)178 (118.4)0.3423
AST (IU/L)104 (180.8)103 (163.1)106 (221.4)0.7930
Causes of cirrhosis
 Hepatitis B327 (22.68%)247 (23.55%)80 (20.36%)0.1977
 Hepatitis C462 (32.04%)340 (32.41%)122 (31.04%)0.6200
 Alcoholism570 (39.53%)408 (38.89%)162 (41.22%)0.4209
Malignancies
 Yes442 (30.65%)315 (30.03%)127 (32.32%)
 No1000 (69.35%)734 (69.97%)266 (67.68%)0.4016
Proved variceal hemorrhage
 Yes949 (65.81%)728 (69.40%)221 (56.23%)<0.0001
 No493 (34.19%)321 (30.60%)172 (43.77%)
Endoscopic treatment
 None473 (32.80%)302 (28.79%)171 (43.51%)<0.0001
 Band ligation655 (45.42%)498 (47.47%)157 (39.95%)
 Sclerotherapy181 (12.55%)141 (13.44%)40 (10.18%)
 Combined18 (1.25%)14 (1.33%)4 (1.02%)
 Ulcer related 115 (7.98%)94 (8.96%)21 (5.34%)
Death
 Yes157 (10.89%)120 (11.44%)37 (9.41%)0.2717
 No1285 (89.11%)929 (88.56%)356 (90.59%)
Duration of hospital stay (day)7.97 (7.5)7.74 (7.2)8.59 (8.1)0.0551
Complications
 All 326 (22.61%)243 (23.16%)83 (21.12%)0.4084
 Repeated endoscopy192 (13.31%)145 (13.82%)47 (11.96%)0.3537
 Operations42 (2.91%)32 (3.05%)10 (2.54%)0.6109
 Balloon tamponade21 (1.46%)18 (1.72%)3 (0.76%)0.1788
 14-day rebleeding102 (7.07%)77 (7.34%)25 (6.36%)0.5185
 30-day all cause mortalities35 (2.43%)25 (2.39%)10 (2.54%)0.8614

Continuous variables were displayed as mean and standard deviation (SD); categorical variables were displayed as numbers and percentage.