International Scholarly Research Notices

Clinical Study

Utilization of Preventive Measures for Glucocorticoid-Induced Osteoporosis among Veterans with Inflammatory Bowel Disease

Associations of clinical variables with calcium and vitamin D prescribing, and BMD testing by univariate analysis.


Variable	Calcium			Vitamin D			BMD
Variable	value	OR	95% CI	value	OR	95% CI	value	OR	95% CI

Age at steroid initiation
Continuous (per year)	0.36			0.69			0.65
≥50 versus <50	0.82			0.21			0.38
Age at IBD diagnosis (per year)	0.33			0.22			0.39
Gender (males versus females)	0.98			0.98			0.55
Race (Caucasian versus African American)	0.88			0.85			0.39
Diagnosis (Crohn's disease versus ulcerative colitis)	0.85			0.63			0.10
IBD duration (per year)	0.76			0.83			0.07
Steroids (budesonide versus prednisone)	0.96			0.69			0.03	0.29	0.10–0.87
Steroid duration (per month)	0.42			0.37			0.49
Prednisone dose (per mg)	0.11			0.13			0.06
Location	0.64			0.82			0.15
BMI <21 kg/m²	0.05	0.26	0.07–1.00	0.06			0.44
Albumin <3.5 g/dL	0.33			0.11			0.04	2.92	1.03–8.28
Year of steroid initiation
≥2006 versus <2006	0.002	4.25	1.72–10.48	0.003	3.81	1.55–9.34	0.002	5.04	1.83–13.92
Continuous (per year)	0.04	1.21	1.01–1.45	0.10			0.002	1.39	1.13–1.72
BMD	0.008	2.42	1.26–4.65	0.01	2.27	1.21–4.27	NA
BMD (excluding abnormal exams)	0.07			0.17			NA