Clinical Study
Infusion Rate Escalation Study of Rituximab in Patients with CD20+ B-Cell Lymphomas: A Single Institution Analysis in Japan
| ā | G1 | G2 | G3 | G4 | Total | ā | | | | | | | | | | |
| Leukocytopenia | 1 | 6 | 1 | 6 | 1 | 6 | 0 | 0 | 3 | 17 | Neutropenia | 1 | 6 | 1 | 6 | 0 | 0 | 1 | 6 | 3 | 17 | Anemia | 2 | 11 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 11 | Infusion reaction | 4 | 22 | 0 | 0 | 0 | 0 | 0 | 0 | 4 | 22 | Conduction disorder | 1 | 6 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 6 | Ventricular arrhythmia | 2 | 11 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 11 | Malaise | 3 | 17 | 0 | 0 | 0 | 0 | 0 | 0 | 3 | 17 | Hypotension | 1 | 6 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 6 | Pharyngitis | 2 | 11 | 1 | 6 | 0 | 0 | 0 | 0 | 3 | 17 | Bronchitis | 0 | 0 | 1 | 6 | 0 | 0 | 0 | 0 | 1 | 6 | Herpes zoster infection | 0 | 0 | 1 | 6 | 0 | 0 | 0 | 0 | 1 | 6 | Diarrhea | 1 | 6 | 1 | 6 | 0 | 0 | 0 | 0 | 2 | 11 | AST increased | 3 | 17 | 0 | 0 | 0 | 0 | 0 | 0 | 3 | 17 | ALT increased | 2 | 11 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 11 | Nausea | 1 | 6 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 6 | Palpitations | 1 | 6 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 6 | Allergic rhinitis | 1 | 6 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 6 | Constipation | 1 | 6 | 1 | 6 | 0 | 0 | 0 | 0 | 2 | 11 | Insomnia | 2 | 11 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 11 | Peripheral neuropathy | 2 | 11 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 11 | Creatinine increased | 1 | 6 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 6 | Acne | 0 | 0 | 1 | 6 | 0 | 0 | 0 | 0 | 1 | 6 | Anorexia | 1 | 6 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 6 |
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AST: aspartate aminotransferase; ALT: alanine aminotransferase.
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