Research Article

Evaluation of Packed-Bed Reactor and Continuous Stirred Tank Reactor for the Production of Colchicine Derivatives

Table 2

Concentration ranges of independent process variables (dissolved oxygen, colchicine concentration, and process time) used in RSM.

FactorNameUnitsTypeMin.Max.āˆ’1 actual+1 actualMeanStd. Dev.

ADO(%)Numeric3.0761.93155032.514.46
BColchicine(g/L)Numeric3.311.75107.52.07
CProcess Time(s)Numeric31.9152.093648424.96