Research Article

Antiallergic and Antiarthritic Effects of Stem Bark Extract of Glyphaea brevis (Spreng) Monachino (Tiliaceae) in Murine Models

Figure 2

Effect of G. brevis extract (GBE) on compound 48/80-induced anaphylaxis in mice. C57BL/6 mice (25–30 g) were pretreated for 1 h with saline, GBE 30, 100, and 300 mg kg−1 ( ). Compound 48/80 was injected (10 mg kg−1, i.p.) and mortality monitored for 1 h after induction of anaphylactic shock. The experimental results were analysed using the Log-rank (Mantel Cox) test and the survival rates were significant *** compared to the saline-treated control mice.
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